the the Neuroprotective Effects of Ethanoic extract of propolis on SH-SY5Y cell line Model of Parkinson’s Disease

Abstract

Background: Parkinson’s disease (PD) is the second most prevalent neurodegenerative disease. There are currently more than five million PD patients worldwide. Up to date, no curing treatment is available. The main characteristics of PD are the degeneration of dopaminergic neurons in the substantia nigra pars compacta and the lack of dopamine in the striatum, which result in the clinical features including tremor, bradykinesia, and muscle stiffness.